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: Gnoni A, Longo S, Gnoni GV, Giudetti AM

Ethics declarations Ethical approval All animal experiments and care were conducted according to Alexandria University, Faculty of Medicines Research Ethics Committee (license number: AU 04230427301)

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* The reason -yfgn and -aglr appear at the end of these drug names is to show that the drugs are distinct from each other and from similar medications that may be created in the future

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