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Some patients report headache, changes in sleep patterns, mild nausea, or mood fluctuation during the first week

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The most common side effects of zonisamide include: dizziness and lightheadedness fatigue and drowsiness language and speech difficulty metallic taste nausea Other possible side effects include: trouble sleeping lack of coordination loss of appetite and weight loss diarrhea double vision mood changes such as depression or irritability difficulty concentrating These symptoms may subside after your body adjusts to the medication