Cell Reports (2018) 10.1016/j.celrep.2018.05.054 Follow-up study showing that p53 mutations (common in cancer cells) confer resistance to FOXO4-DRI, highlighting the p53-dependent mechanism and the importance of functional p53 for the senolytic effect
Research protocols commonly reference CJC-1295 with DAC at 1-2mg per week and Ipamorelin at 100-300mcg per administration, one to three times daily
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