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The study found that treatment with HO-1/bone marrow (BM) MSC-derived exosomes significantly improves cell status and IEC-6 survival, reduces early apoptotic cells, and protects tight junction structures, demonstrated by increased ZO-1in an inflammatory environment

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This repeated injury can lead to esophagitis, characterized by inflammation, erosion, and ulceration of the tissue

[DOI] [PMC free article] [PubMed] [Google Scholar] 32.Javaheri S., Javaheri S., Somers V.K., Gozal D., Mokhlesi B., Mehra R., McNicholas W.T., Zee P.C., Campos-Rodriguez F., Martinez-Garcia M.A., et al