There have been no direct studies comparing Contrave and Wegovy, but we can look at the individual weight loss results for each drug
Semaglutide GLP-1 belongs to a category of drugs known as glucagon-like peptide-1 (GLP-1) receptor agonists, often referred to as incretin mimetics. By imitating the function of GLP-1, a natural hormone in our bodies, Semaglutide GLP-1 plays an important role in controlling blood sugar levels, reducing appetite, and slowing down gastric emptying all of which can contribute to weight loss
The remaining patients usually stay at 1.7 mg long-term because of gastrointestinal side effects
These hormones help signal fullness to the brain after eating, which can reduce cravings and support portion control
Lippincott-Raven, 1997, pp 127-175
Expanding cardiovascular indications for semaglutide: results from the SOUL and STRIDE trials