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First, we examined the expression levels of GLP-1R using immunohistochemistry staining in the livers of patients that were diagnosed with NAFLD by liver biopsy and in normal controls

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The findings warrant further investigation to understand the cellular/molecular mechanisms involved in the improved functional outcome

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Consistent with this, glucagon-stimulation of insulin secretion is decreased in islets isolated from -cell-specific GLP-1R KO mice [173]

A few years ago, this supplement was not available to the general public because the Food and Drug Administration did not approve of it for use on the skin