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c ) TH cell numbers in mutants indicate a significant increase in the SNc ( Trkb Penk-WT , 3462 182

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Diabetes 45(4):385392

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In addition, to help decrease neuroinflammation, a key factor driving PD pathogenesis, GLP-1 RAs modulate immune cell activity and suppress the release of proinflammatory cytokines, such as TNF-, IL-6, and IL-1, all of which play a major role in neuroinflammation