They are all small molecules which act as reversible competitive inhibitors of the catalytic activity of DPP-4 and, when used at the appropriate therapeutic dose, are associated with at least 70% inhibition of plasma DPP-4 activity ( in vivo is likely to be higher, due to dilution of the inhibitor in the ex vivo assay)
A potential confounding factor is a general effect on ingestive behaviors, given that the GLP-1 pathway reduces the levels of the intake of alcohol, addictive drugs, and food
GLP-2 medications are not used for weight loss or diabetes treatment, says Dr
Endocrinology 139 , 44484454 (1998)
How to Get GLP-1 Medication Without Insurance If you dont have insurance, there are still ways to access GLP-1 medications at a lower cost
This suggests the medication acts directly on vascular tissue, not just through body composition changes