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Do not take two doses on the same day to compensate for the missed tablet, as this may increase the risk of adverse effects such as nausea, vomiting, or gastrointestinal discomfort

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Conversely, high oxidative stress can accelerate NAD+ degradation via the enzyme CD38, which consumes NAD+ as part of the inflammatory response

Cahn A, Wiviott SD, Mosenzon O, Murphy SA, Goodrich EL, Yanuv I, et al