Ryu S, Jin M, Lee H-K, Wang M-H, Baek J-S, Cho C-W
Systemic depletion of l-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth
Nevertheless, limitations also exists such as obvious postoperative pain, prolonged healing time, longer hospitalization and extended time of resumed normal work [13, 14]
Signs and symptoms Loose joints Joint pain Stretchy, velvety skin Fragile skin Abnormal scar formation Complications Aortic dissection Joint dislocations Scoliosis Chronic pain Early osteoarthritis Management Obstetrical anesthesia Difficult management, requires multidisciplinary effort High risk of preterm labor, uterine rupture, and hemorrhage Neuraxial anesthesia is relatively contraindicated, may need general anesthesia If vascular subtype recommendations are termination of pregnancy or Cesarean section before 32 weeks Keep in mind Avoid ambulatory surgery in EDS patients Be aware of typical EDS-related emergency-like situations such as difficult airway status, bleeding risks, and organ rupture in specific subtypes Suggested reading Malfait F, Francomano C, Byers P, et al
After reconstitution (mixed with bacteriostatic water) Once you add bacteriostatic water to your GHK-Cu powder, refrigeration becomes mandatory
Always track the date of reconstitution and avoid using vials beyond recommended research storage timelines