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Description

The eligibility criteria for most FDA-approved weight loss drugs are as follows: Body mass index (BMI) of 30 or higher (classified as obesity) Body mass index (BMI) of 27 or higher (classified as overweight) with one weight-related health condition, such as hypertension, hyperlipidemia, heart disease, and high blood cholesterol levels

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Mattson et al., 2007

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Metabolic disorders, such as obesity, T2DM, and insulin resistance, have emerged as significant risk factors for the development and progression of HCC [151]

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Renal and Metabolic Benefits The benefits of GLP-1 agonists extend to renal outcomes, as demonstrated in the SELECT trial

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