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Development of a conditional in vivo model to evaluate the efficacy of small molecule inhibitors for the treatment of Raf-transformed hematopoietic cells

Erythrocytes from knock-out mice that do not express the energy-sensing enzyme AMPK are significantly more susceptible to the eryptotic effect of energy depletion than erythrocytes from wild-type littermates expressing normal levels of AMPK [149]

In some cases, these allergic reactions may result in severe asthma attacks, which can be life threatening

ii) the production technology to be exploited, which dictates the materials to be used and resolution

10.1074/jbc.272.46.29364 J