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33 Nevertheless, ferroptosis has gained significant traction as a mode of cell death in various disease processes, including liver diseases and DILI, especially APAP-induced liver injury

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SREBP1 activation induces stearoyl-CoA desaturase ( SCD1 ) expression, which presumably promotes the accumulation of ferroptosis-inhibitory monounsaturated fatty acids 18 though this connection awaits to be validated by lipidomics