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Neurons, astrocytes, and oligodendrocytes all express it, and IGF-1 signaling has documented roles in neurogenesis, synaptogenesis, myelination, and neuronal survival

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Study Reference Coy DH, Hocart SJ, Murphy WA

Although there is little evidence to support a purely environmental causative agent in the sense of an infectious agent, the autoimmune hypothesis of MS is widely accepted (Korn 2008)

[DOI] [PMC free article] [PubMed] [Google Scholar] 69.Hatch M, Freel RW