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First, we leveraged the All of Us Research Program, a large, diverse, dataset with longitudinal electronic health record data, improving the robustness of the findings to real-world clinical populations with diabetes and/or obesity

While dehydration itself is not typically reported as a direct side effect in clinical trials, the risk stems from the common gastrointestinal side effects that can lead to fluid loss

Animal Studies Wound healing research in rats demonstrated a 64.5% reduction in wound size over 13 days for GHK-treated wounds, versus 45.6% for vehicle-treated and 28.2% for untreated controls

Most focus on substances like steroids and stimulants

Typical trial exclusion criteria for retatrutide studies, consistent with those applied to similar investigational and licensed medicines in this class, have included: pregnancy or breastfeeding (with active contraception requirements during participation)

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