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523 Analysis of gene expression in cortical astrocytes from old mice identified an increase in genes linked to an immune response with a decrease in expression of GFAP and genes related to neuroprotection and neuronal support, 524 and the prominent up-regulation of genes contributing to synapse elimination in astrocytes from aged hippocampus and cerebellum

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Collectively the ex vivo experiments support a direct effect of GLP-1 on the hearts sinus node, which is mediated through the GLP-1 receptor

Lee SH et al

Strength training and a high-protein diet are still your foundation.