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However, FOXO4-DRI treatment significantly reduced the expression of these detrimental SASP factors and, critically, restored the proliferation of GC-1 spg cells in the co-culture system, as evidenced by CCK-8 assays and PCNA expression, without inducing apoptosis in the spermatogonia

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367 Specifically, liraglutide, both alone and in combination with insulin, effectively suppressed the formation of osteoclasts

At twenty-four months, long-term the continuous use group lost 7.4% additional body weight in comparison with the short-term use group