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Description

IGF-1 and its analogs including IGF-1 LR3 are listed under S2 (Peptide Hormones, Growth Factors, Related Substances and Mimetics) and are prohibited at all times, in and out of competition

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10.1172/JCI60433

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Many of the studies available are case reports or clinical trials with small sample sizes or short durations

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Additionally, ER stress activates the NOD-like receptor pyrin domain-containing 3 (NLRP3) inflammasome and the pyroptosis marker GSDMD, further exacerbating intestinal inflammation [85]

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