Viewpoints in JAMA and Annals of Internal Medicine raised their own unanswered questions about how a two-year program winds down
The most common are gastrointestinal: Nausea the most frequently reported side effect, especially during dose increases Vomiting less common than nausea, but can occur during titration Diarrhea typically mild and temporary Constipation some patients experience this instead of or in addition to diarrhea Decreased appetite this is both a therapeutic effect and something patients notice as a side effect These side effects are generally most noticeable in the first few weeks of treatment or after a dose increase, and tend to improve as the body adjusts
The Coming Access Fight The debate over whether to cover GLP-1s in Medicare is really a part of the much larger debate in drug policy about value: Are the drugs we take worth the prices we pay for them
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It binds to its specific receptors on pancreatic beta cells, enhancing insulin secretion in response to postprandial hyperglycemia (Fig
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