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2011 Sep;96(9):E1409-17

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As a result, the increased secondary BAs can activate TGR5, which increases L-cells and GLP-1 secretion by inhibiting the RhoA/ROCK pathway and inducing YAP activation [157, 203]

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How is it different from approved GLP-1 medications

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We do not have definitive data regarding what GLP-1 receptor agonists by themselves do for acne, or other inflammatory dermatologic diseases for that matter

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Gallups survey found nearly 70% of current GLP-1 users take FDA-approved brand-name medications, compared with 19% using the generally cheaper, compounded versions

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