This mechanism involved changes in hepatocyte-macrophage crosstalk and LXR activation, which we identified to be critical for pro-resolving macrophage phenotype and the fibrosis resolution process
Methods: Consecutive patients seen over a 5 month period who were either being seen for f/u of NASH or known Cirrhosis (of any cause) or as new referrals for either abnormal liver function tests, concern for NASH or abnormal imaging of the liver underwent point of care sequential FIBROSCAN imaging to obtain a fibrosis score and CAP value followed by transabdominal US imaging using MACH 40 platform to obtain 2D SWE score, liver viscosity value, liver speed followed by Hepatic Renal Ratio (HRR) value
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(2022) 13:967151.doi: 10.3389/fimmu.2022.967151 171 ZhangPPanYWuSHeYWangJChenLet al
Their function depends on the [Fe-S] binding capacity and not on the reductase activity [154]
Plant glutathione peroxidases: Emerging role of the antioxidant enzymes in plant development and stress responses