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The GLP-1s have multi-organ protective therapies with benefits spanning cardiovascular, kidney, liver, metabolic, and emerging neurologic domains as well

Later, as dormant microbes become active, another wave of die-off may occur

doi: 10.1016/j.pneurobio.2016.10.001 14

H.LiuY.et al (2023a)

The intracellular proteins could reflect transfer from tumor cells to immune cells through extracellular vesicles, mitochondriaplasma membrane interactions 39 or tunneling nanotubes 40 or they could be artifacts from nonspecific binding due to our use of the monoculture (rather than coculture) no-LaccID negative control for data filtering (Fig

Essentially, MOTS-c helps orchestrate a genome-wide response that mimics some benefits of exercise at the cellular level, a phenomenon sometimes called mitohormesis (where a mild stress like exercise leads to stronger cellular function)