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Ko et al., 2018) in a sciatic nerve explants, and the MET inhibitor crizotinib blocks Gab2 phosphorylation in SCs (Shin et al., 2017)

The FDAs Stance and Why It Misses the Mark In 2023, the FDA classified BPC-157 as a Category 2 bulk drug substance , meaning it raises significant safety concerns. The agency specifically cited risks of immunogenicity , peptide-related impurities , and lack of sufficient safety data for human use