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One often overlooked risk is the significant loss of muscle or lean body mass (LBD), which can have profound implications for metabolic health and longevity

In a 68-week clinical trial, patients treated with GLP-1 experienced an average weight loss of 14.9% from their initial body Trusted Source Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial Rubino D, Abrahamsson N, Davies M, et al Go to Source weight

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Dermoscopy shows red-to-black globules or dots, sometimes with a white halo (thrombosed capillaries) (Fig