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According to the authors, These observations present a potential therapeutic target for improved GI pathology during inflammation. The conclusions are published ahead of print in the American Journal of PhysiologyGastrointestinal and Liver Physiology

TABLE 1 Redox changes with fasting, DR, or aging

Psychiatry 11 (1), 353

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Evidence from metabolism studies, case reports and larger systematic retrospective case reviews but no prospective controlled trials demonstrate that following single acute paracetamol overdose , children may be relatively protected from acute liver injury and hepatotoxicity when compared to adults [15, 46, 51,52,53, 58]

In this assay, GSSG-driven roGFP2 oxidation did not depend on the oxidase DsbA (Fig