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Particularly noteworthy, systemic administration might interfere with normal redox balance in other tissues and organs

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doi: 10.1056/NEJMra1807761 [PubMed] 32320796 Gallardo A, Moreno EM, Laffond E, Muoz-Bellido FJ, Gracia-Bara MT, Macias EM, Campanon MV, de Arriba S, Martin C, Sobrino M, Davila I