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Retatrutide for the treatment of obesity, obstructive sleep apnea and the TRIUMPH clinical development program

GLP-1RAs, originally developed for glycemic control, have shown neuroprotective properties in many preclinical studies

In July 2024 , Genentech , a member of the Roche Group announced positive topline results from two arms of an ongoing multi-part Phase I clinical trial for CT-996, an investigational, once-daily, oral small molecule GLP-1 receptor agonist being developed for the treatment of both type 2 diabetes and obesity

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Excluded are defendants, the company's officers and directors at all relevant times, their immediate families, legal representatives, heirs, successors or assigns, and any entity in which defendants have or had a controlling interest

Clinical studies are scarce, highlighting the need for further research to assess bone quality and long-term skeletal outcomes in individuals using GLP-1s