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Moreover, Novo states that no head-to-head trial has compared the highest approved doses of Zepbound and Wegovy

Summary: Retatrutide, as an investigational peptide injectable, should be refrigerated at 2C to 8C in line with general peptide storage principles, but the definitive storage conditions are set by the trial sponsor and site pharmacist, not a publicly available SmPC

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Journal of physiology and pharmacology : an official journal of the Polish Physiological Society , 60 Suppl 7 , 115122

Glia 58 , 831838 (2010)

It carries a black box warning regarding thyroid C-cell tumors based on rodent studies, though no such risk has been documented in humans