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3 If initial therapy with metformin and lifestyle efforts are not adequate to achieve individualized glycemic targets, the guidelines recommend that patients should progress to dual therapy by adding either another oral agent, basal insulin, or an injectable GLP-1 receptor agonist

doi: 10.1038/s41572-020-0204-y 69 KessenbrockKKrumbholzMSchonermarckUBackWGrossWLWerbZet al

1 HIR occurrence relies on increased ROS levels

doi: 10.2174/2211738505666170515113936 [DOI] [PubMed] [Google Scholar] Ladiges Warren

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Therefore, they suggested that the ferroptosis process was inhibited in vitiligo patients after systemic treatment