In a mouse model of diabetes, topiramate effectively protected the brain from diabetes-induced damage by reducing 4-HNE levels and increasing glutathione (GSH) levels (Price et al., 2015)
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Parkinsonism Related Disord (2011) 17:71723.10.1016/j.parkreldis.2011.02.018 92 AllenAMMacGregorDPChaiSYDonnanGADaczmarczykSRichardsonKet alAngiotensin II receptor binding associated with nigrostriatal dopaminergic neurons in human basal ganglia
Once the metal is bound to the glutathione molecule, the resulting complex is much less reactive and can be transported through the bloodstream for eventual removal
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