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As a result, most GLP-1 therapies are delivered through subcutaneous injection, a small needle just under the skin

Lu C, Xu C, Li S, et al

This enhances both the comfort of the procedure and the safety profile of the device by keeping the top layer of the skin safe

MHRA approves GLP-1 receptor agonist semaglutide to reduce risk of serious heart problems in obese or overweight adults

If symptoms are severe or do not improve, a healthcare provider should be consulted

The FDA issued a safety communication in 2024 noting that compounded semaglutide and tirzepatide products had generated adverse event reports including hospitalizations from dosing errors and contamination [10]