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microtubule-associated protein light chain (LC) 3B and nucleoporin p62/SQSTM1 (1:500, GeneTex, Irvine, California, USA)

The genes encoding for these enzymes are positively regulated by the oncogene AKT which acts upstream the transcription factor Nrf2

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Fulminant hepatic failure from drug-induced hepatotoxicity may require liver transplantation

CAS Number: 3054-47-5

The hypoxic response also drives a metabolic shift leading to lactate release, acidification and hepcidin production [55]