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Its mechanism of action is unrelated to the glucose-regulating pathways that drugs like Metformin or GLP-1 agonists target

New data from a massive cohort study of 2 million patients published in Nature Medicine in January 2025, suggest that GLP-1 medications may actually reduce the risk of substance use disorders , including Cannabis Use Disorder (CUD)

The exact biological mechanism by which GLP-1 receptor agonists and dual GIP/GLP-1 receptor agonists like tirzepatide might induce dysesthesia or allodynia is not fully understood

Nutrients , 10 (12), 1876

Regular check-ups with your healthcare provider will let them track your progress

SGLT2 inhibitors and GLP-1 receptor agonists provide distinct cardiorenal protection