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Jensen A, Nielsen ML, Guleria S, Kjaer SK, Heitmann BL, Kesmodel US

The mechanisms underlying IGF-1's tendon repair effects involve activation of the IGF-1 receptor on tenocytes and tendon stem cells, leading to enhanced extracellular matrix synthesis, improved cellular migration to injury sites, and optimized remodeling of repair tissue

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Obesity has emerged as one of the gravest public health challenges of the 21st century

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