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Humans express two genes that generate glucose-6-phosphate dehydrogenase activity, the X-linked G6PD gene and an autosomal gene identified as H6PD (hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase)

2 Methods 2.1 Animals and procedures The animal experimental procedures were approved by the Animal Care and Use Committee of Oujiang Laboratory (SYXK2023-0047, OJLAB22121609), and were carried out in strict accordance with the National Institutes of Health Guidelines for the Use of Laboratory Animals

Unavoidably, microglial TBK1-KO leads to focal microglial activation and both CD8 + and CD8 T cells infiltration in the basal ganglia (Lenoel et al., 2025)

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