This pool included several add-on trials (metformin HCl alone and in combination with a dipeptidyl peptidase-4 [DPP4] inhibitor and metformin HCl , or insulin and metformin HCl, 2 initial combination with metformin HCl trials, and 2 trials of patients with CVDand type 2 diabetes mellitus who received their usual treatment [with metformin HCl as background therapy])
Ongoing care: Youll message your provider for refills and dose adjustments
Lin SH, Komaki R, Liao Z, Wei C, Myles B, Guo X, Palmer M, Mohan R, Swisher SG , Hofstetter WL, Ajani JA, Cox JD
For NAION, the risk appears higher with GLP-1 users who are obese and diabetic, though the available early data is incomplete. He believes the risk may be higher in patients with small optic nerve cups, sometimes described as a disc at risk. Regarding neovascular age-related macular degeneration, he said signals exist, though causality has not been established
JACC Basic Transl Sci 3:503517 Aluja D, Delgado-Toms S, Ruiz-Meana M, Barrabs JA, Inserte J (2022) Calpains as potential therapeutic targets for myocardial hypertrophy
Understanding the relationship between these medications and reflux helps patients and clinicians optimize treatment while managing potential gastrointestinal effects
