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These hormones, known collectively as incretins, are secreted by the gut in response to nutrient ingestion and play crucial roles in metabolic regulation

Originally developed for type 2 diabetes management, it works by mimicking natural hunger hormones in the brain to slow down stomach emptying and curb your appetite, making it easier to stick to a calorie deficit and achieve significant, sustainable weight loss

However, Lillys tirzepatide has some edges (e.g., trial efficacy and investor perception of pipeline strength) that have allowed Lilly to close the gap

However, we should also note that too much fiber, particularly insoluble fiber, can cause constipation, along with more gas, bloating, farting, and burping

Picha, K

doi:10.1001/jamapediatrics.2024.1576 4