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230 This modification can improve the resistance of nucleic acids to nucleases, enhance blood stability, reduce renal clearance, and prolong the circulation time of drugs in vivo by improving their binding to plasma proteins
What Ipamorelin doesn't do: Does not significantly increase cortisol (stress hormone) Does not significantly increase prolactin Does not cause the intense hunger spikes seen with GHRP-6 Does not disrupt other hormonal axes This selectivity is Ipamorelin's defining advantage
doi: 10.1016/S0009-9120(01)00196-5
Thats why it can feel like everyone is doing it
Proteins were digested after desalting (Amicon Ultra 3 kDa MWCO, Millipore), then subjected to heat denaturation (80 C), reduction, alkylation, and trypsin digestion (1:20 ratio trypsin:protein (w/w))