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The most common serious laboratory abnormalities (grade 3 or 4, 2%) were leukopenia, anemia, decreased phosphate, hypocalcemia, hyponatremia, increased liver enzymes, thrombocytopenia, and increased alkaline phosphatase levels (NCT03037385) [36,37]

[DOI] [PMC free article] [PubMed] [Google Scholar] 82

While consuming a diet rich in Glutathione or taking supplements can increase the levels of Glutathione in the body, the efficacy of this antioxidant diminishes as it passes through the digestive system

Nat Rev Drug Discov 2:214221 Hayes HC, Luk LY, Tsai Y-H (2021) Approaches for peptide and protein cyclisation

This makes it part of a unique class of peptides called mitochondrial-derived peptides (MDPs) small proteins that act as signaling molecules to regulate metabolism and cellular stress responses

We have also evaluated the antioxidant effect of NAC under different storage conditions in vitro