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When excessive glutamate is released from the presynaptic, it stimulates the postsynaptic ionotropic glutamate receptors (iGluRs) and metabotropic glutamate receptors (mGluRs)

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[17] FOXO's activation of these pathways produces an increase in lifespan for worms, flies, mice

The basement membrane covers the adventitial surface of ECs and extends around capillaries but separates postcapillaries at venules

doi: 10.1007/s00430-021-00727-0 167 LinY.XuY.ZhangZ

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