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The analysis of brain growth and myelination in a transgenic mouse line that overexpresses IGF-1 indicate that IGF-1 is a potent inducer of brain growth and myelination in vivo

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Physiologically, OAT4 facilitates uric acid excretion in the proximal tubule by orchestrating ion exchange processes such as PAH/Cl-, PAH/ES, and potentially PAH/UA interactions

Several studies were performed to evaluate the effects of several antidiabetic drugs like incretins, thiazolidines, metformin, and intranasal insulin in the treatment of AD [9]