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7,8 Moreover, eating a healthy diet, such as the Dietary Approaches to Stop Hypertension (DASH) or Mediterranean diet, and lowering the intake of sodium, phosphorus and sometimes protein may help protect kidney function

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16 However, islet beta-cells can produce and secrete insulin in an incretin-independent manner as long as blood glucose levels are 5mM or higher

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Healthcare professionals prescribing Wegovy should conduct a thorough medical history before initiation, including assessment of: Previous or current neurological conditions History of pancreatitis or gallbladder disease Diabetic retinopathy (in patients with diabetes) Renal function Concurrent medications that may interact Regular monitoring during treatment should include: Assessment of weight loss progress and tolerability Blood glucose monitoring (particularly in patients with diabetes) Review of gastrointestinal symptoms and hydration status Evaluation of any new or worsening symptoms The European Medicines Agency (EMA) and MHRA require manufacturers to submit periodic safety update reports, which analyse all available safety data from clinical trials, post-marketing surveillance, and published literature