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These provide evidence for general biological principles (GH/IGF-1 axis supporting musculoskeletal health, collagen building blocks beneficial) lending credibility to targeted peptide interventions though not direct proof

Paraquat neurotoxicity is distinct from that of MPTP and rotenone

Molecular recognition of two endogenous hormones by the human parathyroid hormone receptor-1

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No significant differences between control and PXN LOW were observed in aged animals, although a trend was present ( P = 0.07)

Questions, however, remain about potential adverse effects, as, paradoxically, the transient presence of senescent cells could be beneficial during embryogenesis and wound healing.82 A more conservative approach involves the use of molecules with senomorphic effects capable of modulating the counterproductive nature of senescent cells and restarting cell proliferation