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The implications of this when using incretins for weight loss are somewhat different compared to use for managing hormones in type 1 diabetes

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Real-world evidence suggests favorable cardiovascular effects, with some retrospective analyses showing tirzepatide may reduce major cardiovascular events by approximately 14% compared to semaglutide

Combined with consistent strength training, sufficient protein preserves the underlying muscle architecture that keeps the face looking lifted and full, even as subcutaneous fat decreases

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It inhibits glucagon release from the alpha cells, which means it is working on both ends of the glucose regulation equation simultaneously