At best, it may serve as one piece of a larger, clinician-guided plan, but it should never be treated as a substitute for the fundamentals
5 mg/mL concentration: 50 units = 2.5 mg (starting dose, weeks 1-4) 10 mg/mL concentration: 50 units = 5 mg (moderate dose, weeks 5-8) 15 mg/mL concentration: 50 units = 7.5 mg (mid-range dose, weeks 9-12) 17 mg/mL concentration: 50 units = 8.5 mg (between standard tiers) 20 mg/mL concentration: 50 units = 10 mg (high dose, weeks 13-16) 30 mg/mL concentration: 50 units = 15 mg (maximum dose, week 21+) Notice the pattern
So far, no Tolerable Upper Intake Level (UL) has been established for B12
Are there cases where treatment is not recommended
Antioxid Redox Signal 26:718742 Gajecki D, Gawry J, Szahidewicz-Krupska E, Doroszko A (2022) Role of erythrocytes in nitric oxide metabolism and paracrine regulation of endothelial function
topical concentration and application frequency are individualized based on the indication and formulation
