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doi: 10.1016/j.joca.2020.02.103 21

Acute exacerbation was defined as significant respiratory deterioration including clinical worsening of dyspnoea, hypoxemia, or the worsening or severe impairment of gas exchange characterized by new bilateral GGO /consolidation superimposed on a background pattern consistent with an ILD pattern not fully explained by cardiac failure or fluid overload 47,48

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This method can be particularly beneficial for individuals with absorption issues or those who may not be getting enough B12 through diet alone