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In a study involving healthy non-diabetic subjects, daily intake of a Lactobacillus reuteri SD5865 strain for 8 weeks resulted in an increase of GLP-1 secretion in the intestines, which was accompanied by elevated plasma insulin and C-peptide levels [109]

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The first approach is targeting hepatic fat accumulation

These effects typically emerge during dose escalation and often diminish over time as the body adapts to treatment

Mansur RB, Ahmed J, Cha DS, et al