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Most RCTs failed to demonstrate a significant association between GLP-1 RAs and the occurrence of pancreatitis or pancreatic cancer, primarily because of their short duration and insufficient design for evaluating such risks

Participants reported decreased food cravings and improved control over eating

------------------------------------- Niacinamide (Vitamin B3): Niacinamide is the water soluble form of niacin, an essential vitamin for healthy cell metabolism and is part of the B group

Minimal effect on ghrelin, making it well-tolerated

Ferrous iron (Fe 2+ ) catalyzes the Fenton reaction with hydrogen peroxide, generating hydroxyl radicals ( OH) that extract hydrogen atoms from bis-allylic carbons of polyunsaturated fatty acids (PUFAs)

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