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Discussion To identify emerging senolytics, we screened a library of electrophilic compounds, which can target proteins through covalent bond formation

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Atassi N, Xu M, Triantafyllou C, Keil B, Lawson R, Cernasov P, et al

When bound to their specific ligands, different CLRs can differentially influence cellular processes such as endocytosis and phagocytosis, as well as modulate pro-inflammatory or anti-inflammatory outcomes, a function primarily determined by their generalized signaling systems

Additionally, in our laboratory, Gpx4 fl/fl Ksp Cre-ERT2 mice subjected to Tamoxifen induction (100 mg/kg) developed severe tubulointerstitial damage and acute tubular necrosis, accompanied by a marked impairment of renal function as early as day 5 post-induction (Fig

A total of only 1L of product is permitted