Supplementation studies indicate that Se can improve TSH levels in Se-deficient individuals with subclinical hypothyroidism
The tissue and cell disruption during processing (e.g., mixing, cutting, crushing, freezing/thawing, and high pressure treatment) makes native polyglutamyl folates accessible for endogenous conjugases (-glutamyl hydrolases) and results in the hydrolysis to monoglutamyl folates in vegetables (e.g., leeks, cauliflower, broccoli, spinach, soybeans, green beans, cowpea leaves, turnip, and carrot) and fruits (e.g., orange, papaya, sweet cherry, strawberry, and blackberry)
A licensed clinician can prescribe after reviewing your intake and confirming eligibility
Katagiri, T., & Watabe, T
Zhang HX, Zhang Y, Yin H
Due to these risks, it should only be used under a doctors care